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| The relationship between weight loss and interleukin 6 in non-small-cell lung cancer |
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| Author(s): Scott HR, McMillan DC, Crilly A, McArdle CS, Milroy R |
| Source: BRITISH JOURNAL OF CANCER Volume: 73 Issue: 12 Pages: 1560-1562 Published: JUN 1996 |
| Times Cited: 53 References: 22 |
| Abstract: Markers of the inflammatory response interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n=21) with and without weight loss (>5%). There were significant increases in circulating C-reactive protein (P<0.001), interleukin 6 (P<0.01) and platelets (P<0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r=.0785, P<0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC. |
| Document Type: Article |
| Language: English |
| Reprint Address: Scott, HR (reprint author), STOBHILL NHS TRUST, DEPT RESP MED, GLASGOW G21 3UW, LANARK SCOTLAND |
Addresses:
1. UNIV GLASGOW, ROYAL INFIRM, DEPT SURG, GLASGOW G31 2ER, LANARK SCOTLAND 2. UNIV GLASGOW, ROYAL INFIRM, DEPT MED, GLASGOW G31 2ER, LANARK SCOTLAND |
| Publisher: STOCKTON PRESS, HOUNDMILLS, BASINGSTOKE, HAMPSHIRE, ENGLAND RG21 6XS |
| Subject Category: Oncology |
| IDS Number: UQ950 |
| ISSN: 0007-0920 |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |