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The yeast genome project: What did we learn?
Author(s): Dujon B
Source: TRENDS IN GENETICS    Volume: 12    Issue: 7    Pages: 263-270    Published: JUL 1996  
Times Cited: 297     References: 42     
Abstract: The bakers' yeast, Saccharomyces cerevisiae, a microorganism of major importance for bioindustries, and one of the favored model organisms for basic biological research, is the first eukaryote whose genome is entirely sequenced. Beyond the wealth of novel biological information, it is the extent of what remains to be understood in the genome of a simple unicellular organism that is the most striking result: a significant proportion of yeast genes are orphans of unpredictable function. Offering the possibility of large-scale reverse genetics, yeast will be a powerful model for post-sequencing studies. But geneticists are now faced with the difficulty of asking novel questions.
Document Type: Review
Language: English
Reprint Address: Dujon, B (reprint author), INST PASTEUR, UNITE GENET MOL LEVURES, CNRS URA 1149, 25 RUE DR ROUX, F-75724 PARIS 15, FRANCE
Addresses:
1. UNIV PARIS 06, UPR 927, F-75724 PARIS 15, FRANCE
Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB
Subject Category: Genetics & Heredity
IDS Number: UW031
ISSN: 0168-9525
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