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Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii
Author(s): Bult CJ, White O, Olsen GJ, Zhou LX, Fleischmann RD, Sutton GG, Blake JA, FitzGerald LM, Clayton RA, Gocayne JD, Kerlavage AR, Dougherty BA, Tomb JF, Adams MD, Reich CI, Overbeek R, Kirkness EF, Weinstock KG, Merrick JM, Glodek A, Scott JL, Geoghagen NSM, Weidman JF, Fuhrmann JL, Nguyen D, Utterback TR, Kelley JM, Peterson JD, Sadow PW, Hanna MC, Cotton MD, Roberts KM, Hurst MA, Kaine BP, Borodovsky M, Klenk HP, Fraser CM, Smith HO, Woese CR, Venter JC
Source: SCIENCE    Volume: 273    Issue: 5278    Pages: 1058-1073    Published: AUG 23 1996  
Times Cited: 1,849     References: 67     
Abstract: The complete 1.66-megabase pair genome sequence of an autotrophic archaeon, Methanococcus jannaschii, and its 58- and 16-kilobase pair extrachromosomal elements have been determined by whole-genome random sequencing. A total of 1738 predicted protein-coding genes were identified; however, only a minority of these (38 percent) could be assigned a putative cellular role with high confidence. Although the majority of genes related to energy production, cell division, and metabolism in M. jannaschii are most similar to those found in Bacteria, most of the genes involved in transcription, translation, and replication in M. jannaschii are more similar to those found in Eukaryotes.
Document Type: Article
Language: English
Addresses:
1. INST GENOM RES, ROCKVILLE, MD 20850 USA
2. UNIV ILLINOIS, DEPT MICROBIOL, CHAMPAIGN, IL 61801 USA
3. ARGONNE NATL LAB, DIV MATH & COMP SCI, ARGONNE, IL 60439 USA
4. SUNY BUFFALO, DEPT MICROBIOL, BUFFALO, NY 14214 USA
5. GEORGIA INST TECHNOL, SCH BIOL, ATLANTA, GA 30332 USA
6. JOHNS HOPKINS UNIV, SCH MED, DEPT MOL BIOL & GENET, BALTIMORE, MD 21205 USA
Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005
Subject Category: Multidisciplinary Sciences
IDS Number: VD428
ISSN: 0036-8075
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