| | |  | | | | Record from Web of Science® | | | | | | |
| Fast events in protein folding |
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| Author(s): Eaton WA, Thompson PA, Chan CK, Hagen SJ, Hofrichter J |
| Source: STRUCTURE Volume: 4 Issue: 10 Pages: 1133-1139 Published: OCT 15 1996 |
| Times Cited: 65 References: 53 |
| Abstract: Understanding how proteins fold is one of the central problems in biochemistry. A new generation of kinetic experiments has emerged to investigate the mechanisms of protein folding on the previously inaccessible submillisecond time scale. these experiments provide the first glimpse of processes such as secondary structure formation, local hydrophobic collapse, global collapse to compact denatured states, and fast barrier crossings to the native state. Key results are summarized and discussed in terms of the statistical energy landscape theory of protein folding. |
| Document Type: Article |
| Language: English |
| Reprint Address: Eaton, WA (reprint author), NIDDKD, NIH, CHEM PHYS LAB, BLDG 5, BETHESDA, MD 20892 USA |
| Publisher: CURRENT BIOLOGY LTD, 34-42 CLEVELAND STREET, LONDON, ENGLAND W1P 6LB |
| Subject Category: Biochemistry & Molecular Biology; Biophysics; Cell Biology |
| IDS Number: VP148 |
| ISSN: 0969-2126 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |