| | |  | | | | Record from Web of Science® | | | | | | |
| Dielectrophoresis: Using inhomogeneous AC electrical fields to separate and manipulate cells |
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| Author(s): Pethig R |
| Source: CRITICAL REVIEWS IN BIOTECHNOLOGY Volume: 16 Issue: 4 Pages: 331-348 Published: 1996 |
| Times Cited: 136 References: 56 |
| Abstract: Dielectrophoresis is the motion of particles caused by electrical polarization effects in inhomogeneous (nonuniform) electric fields. Unlike electrophoresis, the particles do not require a net electrical charge for motion to occur and AC rather than DC fields are employed to exploit the dielectric properties of the particles. Factors controlling the effective dielectric properties of cells and microorganisms include electrical double layers associated with surface charges, the conductivity and permittivity of their membranes and any cell walls, and their morphologies and structural architectures. In recent years, several laboratories have developed separation and manipulation techniques for cells and microorganisms based on dielectrophoresis, using both static and traveling AC fields. In this article, the basic physical factors influencing the dielectrophoretic behavior of particles are outlined, and ways in which these can be employed to achieve selective separation of cells and microorganisms are described. |
| Document Type: Review |
| Language: English |
| Reprint Address: Pethig, R (reprint author), UNIV WALES, INST MOL & BIOMOL ELECT, BANGOR LL57 1UT, GWYNEDD WALES |
| Publisher: CRC PRESS INC, 2000 CORPORATE BLVD NW, JOURNALS CUSTOMER SERVICE, BOCA RATON, FL 33431 |
| Subject Category: Biotechnology & Applied Microbiology |
| IDS Number: WA932 |
| ISSN: 0738-8551 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |