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Marrow stromal cells as steam cells for nonhematopoietic tissues
Author(s): Prockop DJ
Source: SCIENCE    Volume: 276    Issue: 5309    Pages: 71-74    Published: APR 4 1997  
Times Cited: 1,707     References: 89     
Abstract: Marrow stromal cells can be isolated from other cells in marrow by their tendency to adhere to tissue culture plastic: The cells have many df the characteristics of stem cells for tissues that can roughly be defined as mesenchymal, because they can be differentiated in culture into osteoblasts, chondrocytes, adipocytes, and even myoblasts. Therefore, marrow stromal cells present an intriguing model for examining the differentiation of stem cells. Also, they have several characteristics that make them potentially useful for cell and gene therapy.
Document Type: Article
Language: English
Reprint Address: Prockop, DJ (reprint author), ALLEGHENY UNIV HLTH SCI, CTR GENE THERAPY, MCP HAHNEMANN SCH MED, 245 N 15 ST, MAIL STOP 421, PHILADELPHIA, PA 19102 USA
Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005
Subject Category: Multidisciplinary Sciences
IDS Number: WR386
ISSN: 0036-8075
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