| | |  | | | | Record from Web of Science® | |  |  | | |  |
| The ribosome at higher resolution - The donut takes shape |
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| Author(s): Frank J |
| Source: CURRENT OPINION IN STRUCTURAL BIOLOGY Volume: 7 Issue: 2 Pages: 266-272 Published: APR 1997 |
| Times Cited: 18 References: 61 |
| Abstract: Major new results in the 3D cryoimaging of ribosomes have advanced our understanding of ribosomal structure and function. For the first time, 3D difference maps have been used to image tRNA molecules in situ. With this new technology, the stage is set for detailed ligand-binding experiments that explore the binding states of elongation factors and tRNA, and that pinpoint locations of proteins and RNA on the surface of the ribosome. |
| Document Type: Article |
| Language: English |
| Reprint Address: Frank, J (reprint author), NEW YORK STATE DEPT HLTH, WADSWORTH CTR LABS & RES, POB 509, EMPIRE STATE PLAZA, ALBANY, NY 12201 USA |
Addresses:
1. SUNY ALBANY, DEPT BIOMED SCI, ALBANY, NY 12201 USA |
| Publisher: CURRENT BIOLOGY LTD, 34-42 CLEVELAND STREET, LONDON, ENGLAND W1P 6LB |
| Subject Category: Biochemistry & Molecular Biology; Cell Biology |
| IDS Number: WT192 |
| ISSN: 0959-440X |
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| |  |  |  |  | | | | Record from Web of Science® | |  |  | | | | | | |