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Cancer vaccines based on the identification of genes encoding cancer regression antigens
Author(s): Rosenberg SA
Source: IMMUNOLOGY TODAY    Volume: 18    Issue: 4    Pages: 175-182    Published: APR 1997  
Times Cited: 308     References: 59     
Abstract: The adoptive transfer of tumor-infiltrating lymphocytes (TILs) can mediate the regression of metastatic melanoma in humans. The genes encoding the antigens recognized by these TILs have been cloned and characterized. Here, Steven Rosenberg reviews how these genes and gene products are being used to develop new immunotherapies for the treatment of patients with cancer.
Document Type: Review
Language: English
Reprint Address: Rosenberg, SA (reprint author), NCI, NIH, BETHESDA, MD 20892 USA
Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB
Subject Category: Immunology
IDS Number: WU363
ISSN: 0167-5699
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