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A molecular view of microbial diversity and the biosphere
Author(s): Pace NR
Source: SCIENCE    Volume: 276    Issue: 5313    Pages: 734-740    Published: MAY 2 1997  
Times Cited: 945     References: 61     
Abstract: Over three decades of molecular-phylogenetic studies, researchers have compiled an increasingly robust map of evolutionary diversification showing that the main diversity of life is microbial, distributed among three primary relatedness groups or domains: Archaea, Bacteria, and Eucarya. The general properties of representatives of the three domains indicate that the earliest life was based on inorganic nutrition and that photosynthesis and use of organic compounds for carbon and energy metabolism came comparatively later. The application of molecular-phylogenetic methods to study natural microbial ecosystems without the traditional requirement for cultivation has resulted in the discovery of many unexpected evolutionary lineages; members of some of these lineages are only distantly related to known organisms but are sufficiently abundant that they are likely to have impact on the chemistry of the biosphere.
Document Type: Article
Language: English
Reprint Address: Pace, NR (reprint author), UNIV CALIF BERKELEY, DEPT PLANT & MICROBIAL BIOL, BERKELEY, CA 94720 USA
Addresses:
1. UNIV CALIF BERKELEY, DEPT MOL & CELL BIOL, BERKELEY, CA 94720 USA
Publisher: AMER ASSOC ADVANCEMENT SCIENCE, 1200 NEW YORK AVE, NW, WASHINGTON, DC 20005
Subject Category: Multidisciplinary Sciences
IDS Number: WW900
ISSN: 0036-8075
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