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Double identity for proteins of the Bcl-2 family
Author(s): Reed JC
Source: NATURE    Volume: 387    Issue: 6635    Pages: 773-776    Published: JUN 19 1997  
Times Cited: 1,114     References: 40     
Abstract: Bcl-2 is an oncogenic protein that acts by inhibiting programmed cell death. The mechanisms used by this and related anti-apoptotic proteins to protect cells from cytotoxic stimuli are now emerging, with the discovery that Bcl-2 can function both as an ion channel and as an adaptor or docking protein.
Document Type: Article
Language: English
Reprint Address: Reed, JC (reprint author), BURNHAM INST, PROGRAM APOPTOSIS & CELL DEATH RES, 10901 N TORREY PINES RD, LA JOLLA, CA 92037 USA
Publisher: MACMILLAN MAGAZINES LTD, PORTERS SOUTH, 4 CRINAN ST, LONDON, ENGLAND N1 9XW
Subject Category: Multidisciplinary Sciences
IDS Number: XF144
ISSN: 0028-0836
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