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| Gingival squamous cell carcinoma in a patient with chronic graft-versus-host disease |
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| Author(s): Otsubo H, Yokoe H, Miya T, Atsuta F, Miura N, Tanzawa H, Sato K |
| Source: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS Volume: 84 Issue: 2 Pages: 171-174 Published: AUG 1997 |
| Times Cited: 19 References: 17 |
| Abstract: This article describes a gingival squamous cell carcinoma that developed in a 21-year-old woman who received a bone marrow transplant at the age of 16 from her human leukocyte antigen-identical sister as treatment for severe aplastic anemia. Thirty days after transplantation, she presented with cutaneous erythema as a result of acute graft-versus-host disease, and this subsequently evolved into chronic graft-versus-host disease. A lichenoid white plaque of the gingiva developed shortly thereafter, and it began to increase in size rapidly 4 years posttransplantation. Biopsy indicated squamous cell carcinoma arising in this region, apparently associated with chronic graft-versus-host disease. Few reports have described a secondary solid malignancy involving the oral cavity of young adults after bone marrow transplantation. |
| Document Type: Article |
| Language: English |
Addresses:
1. CHIBA UNIV, SCH MED, DEPT ORAL SURG, CHUO KU, CHIBA 280, JAPAN
2. CHIBA UNIV, SCH MED, DEPT PEDIAT, CHIBA 280, JAPAN |
| Publisher: MOSBY-YEAR BOOK INC, 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 |
| Subject Category: Dentistry, Oral Surgery & Medicine |
| IDS Number: XR145 |
| ISSN: 1079-2104 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |