| Pharmaceutical innovation between scientific opportunities and economic constraints |
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| Author(s): Drews J, Ryser S |
| Source: DRUG DISCOVERY TODAY Volume: 2 Issue: 9 Pages: 365-372 Published: SEP 1997 |
| Times Cited: 15 References: 12 |
| Abstract: New drugs are only developed when sales expectations appear to match the rising expenditures for development. The repertoire of diseases that are seriously addressed by large pharmaceutical companies is shrinking, Genomics offers the promise of inventing and developing more selective therapies for a large number of diseases, but such increases in selectivity almost inevitably lead to therapeutics aimed at smaller patient populations. Scientific opportunity on the one hand and economic constraints on the other are forcing pharmaceutical R&D in different directions. This study tries to quantify the problem and to identify mechanisms through which the apparent conflict may be resolved. |
| Document Type: Review |
| Language: English |
| Reprint Address: Drews, J (reprint author), HOFFMANN LA ROCHE INC, 340 KINGSLAND ST, NUTLEY, NJ 07110 USA |
Addresses:
1. HOFFMANN LA ROCHE AG, CH-4070 BASEL, SWITZERLAND |
| Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB |
| Subject Category: Pharmacology & Pharmacy |
| IDS Number: XR613 |
| ISSN: 1359-6446 |