| | |  | | | | Record from Web of Science® | | | | | | |
| Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways |
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| Author(s): Barth AI, Nathke IS, Nelson WJ |
| Source: CURRENT OPINION IN CELL BIOLOGY Volume: 9 Issue: 5 Pages: 683-690 Published: OCT 1997 |
| Times Cited: 381 References: 93 |
| Abstract: Cadherins play important roles in cell-cell adhesion during tissue differentiation. Cadherins are linked to the actin cytoskeleton by catenins (beta-catenin/armadillo, plakoglobin, and alpha-catenin). Recent results show that beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases and phosphatases and Wnt/Wingless. Interplay between these cytoskeletal complexes and signaling pathways may regulate morphogenesis. |
| Document Type: Article |
| Language: English |
| Reprint Address: Barth, AI (reprint author), STANFORD UNIV, SCH MED, BECKMAN CTR MOL & GENET MED, DEPT CELLULAR & MOL PHYSIOL, B121, STANFORD, CA 94305 USA |
| Publisher: CURRENT BIOLOGY LTD, 34-42 CLEVELAND STREET, LONDON, ENGLAND W1P 6LB |
| Subject Category: Cell Biology |
| IDS Number: XX922 |
| ISSN: 0955-0674 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |