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Applications of dielectrophoresis in biotechnology
Author(s): Pethig R, Markx GH
Source: TRENDS IN BIOTECHNOLOGY    Volume: 15    Issue: 10    Pages: 426-432    Published: OCT 1997  
Times Cited: 131     References: 44     
Abstract: Recent progress in the development of microelectrode structures has led to new techniques for the dielectrophoretic characterization and sorting of cells, microorganisms and other bioparticles using nonuniform AC electric fields. These methods utilize differences in the dielectric polarizabilities of cells for their effectiveness, and factors controlling such properties include the conductivity and permittivity of membranes and any cell walls, electrical double layers associated with surface charges, cell morphologies, and internal structures. Applications of dielectrophoresis have included the selective spatial manipulation and separation of mixtures of bacteria, viable and unviable cells, cancerous and normal cells, and red and white blood cells.
Document Type: Article
Language: English
Reprint Address: Pethig, R (reprint author), UNIV COLL N WALES, INST MOL & BIOMOL ELECT, DEAN ST, BANGOR LL57 1UT, GWYNEDD WALES
Addresses:
1. UNIV MANCHESTER, INST SCI & TECHNOL, DEPT CHEM ENGN, MANCHESTER M60 1QD, LANCS ENGLAND
Publisher: ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, OXON, ENGLAND OX5 1GB
Subject Category: Biotechnology & Applied Microbiology
IDS Number: YA283
ISSN: 0167-7799
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