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A novel RNA-binding motif in influenza A virus non-structural protein 1
Author(s): Chien CY, Tejero R, Huang YP, Zimmerman DE, Rios CB, Krug RM, Montelione GT
Source: NATURE STRUCTURAL BIOLOGY    Volume: 4    Issue: 11    Pages: 891-895    Published: NOV 1997  
Times Cited: 42     References: 24     
Abstract: The solution NMR structure of the RNA-binding domain from influenza virus non-structural protein 1 exhibits a novel dimeric six-helical protein fold, Distributions of basic residues and conserved salt bridges of dimeric NS1(1-73) suggest that the face containing antiparallel helices 2 and 2' forms a novel arginine-rich nucleic acid binding motif.
Document Type: Letter
Language: English
Addresses:
1. RUTGERS STATE UNIV, CTR ADV BIOTECHNOL & MED, PISCATAWAY, NJ 08854 USA
2. RUTGERS STATE UNIV, DEPT MOL BIOL & BIOCHEM, PISCATAWAY, NJ 08854 USA
3. UNIV VALENCIA, DEPT QUIM FIS, E-46100 BURJASSOT, VALENCIA SPAIN
Publisher: NATURE PUBLISHING CO, 345 PARK AVE SOUTH, NEW YORK, NY 10010-1707
Subject Category: Biochemistry & Molecular Biology; Biophysics; Cell Biology
IDS Number: YE159
ISSN: 1072-8368
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