| | |  | | | | Record from Web of Science® | | | | | | |
| MicroRNAs: Genomics, biogenesis, mechanism, and function |
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| Author(s): Bartel DP |
| Source: CELL Volume: 116 Issue: 2 Pages: 281-297 Published: JAN 23 2004 |
| Times Cited: 2,837 References: 132 |
| Abstract: MicroRNAs (miRNAs) are endogenous similar to22 nt RNAs that can play important regulatory roles in animals and plants by targeting mRNAs; for cleavage or translational repression. Although they escaped notice until relatively recently, miRNAs comprise one of the more abundant classes of gene regulatory molecules in multicellular organisms and likely influence the output of many protein-coding genes. |
| Document Type: Review |
| Language: English |
| Reprint Address: Bartel, DP (reprint author), Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA |
Addresses:
1. Whitehead Inst Biomed Res, Cambridge, MA 02142 USA
2. MIT, Dept Biol, Cambridge, MA 02139 USA |
| Publisher: CELL PRESS, 1100 MASSACHUSETTS AVE, CAMBRIDGE, MA 02138 USA |
| Subject Category: Biochemistry & Molecular Biology; Cell Biology |
| IDS Number: 768KG |
| ISSN: 0092-8674 |
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| | | | | | | | | Record from Web of Science® | | | | | | | | | |